Wisdom defined (sort of) -- What is wisdom? -- The wisest man in the world : the philosophical roots of wisdom -- Heart and mind : the psychological roots of wisdom -- Eight neural pillars of wisdom -- Emotional regulation : the art of coping -- Knowing what's important : the neural mechanism of establishing value and making a judgment -- Moral reasoning : the biology of judging right from wrong -- Compassion : the biology of loving-kindness and empathy -- Humility : the gift of perspective -- Altruism : social justice, fairness, and the wisdom of punishment -- Patience : temptation, delayed gratification, and the biology of learning to wait for larger rewards -- Dealing with uncertainty : change, meta-wisdom, and the vulcanization of the human brain -- Becoming wise -- Youth, adversity, and resilience : the seeds of wisdom -- Older and wiser : the wisdom of aging -- Classroom, board room, bedroom, back room : everyday wisdom in our everyday world -- Dare to be wise : does wisdom have a future?